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high exposure to organophosphate flame retardants in infants

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high exposure to organophosphate flame retardants in infants

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high exposure to organophosphate flame retardants in infants

2015-11-19 · Infants may have greater exposure due to greater contact with these products, yet little is known about levels of exposure or the factors contributing to higher exposure. We recruited children age 2–18 months from North Carolina to investigate PFR exposure (n = 43; recruited 2014–2015).


Organophosphate flame retardants (OPFR) and replacement brominated flame retardants (RBFR) are ubiquitous in indoor dust during the polybrominated diphenyl ether (PBDE) phase-out, and recent investigations reported significantly high concentrations of OPE compounds in indoor dust.[22,23] Two novel OPE groups owning structures


Urinary metabolites of organophosphate flame retardants in 0–5-year-old children: Potential exposure risk for inpatients and home-stay infants Author: Zhang, Bo , Lu, Shaoyou ,


Exposure to organophosphate flame retardants in spray polyurethane foam applicators: Role of dermal exposure. Bello A(1), Carignan CC(2), Xue Y(3), Stapleton HM(4), Bello D(5). Author information: (1)University of Massachusetts Lowell, Department of Public Health, Zuckerberg College of Health Sciences, Lowell, MA 01854, United States.


Organophosphate flame retardants (OPFRs) are common replacements for the phased-out polybrominated diphenyl ethers (PBDEs) and have been detected at high concentrations in environmental samples. OPFRs are structurally similar to organophosphate pesticides and may adversely affect the developing nervous system.


2017-11-27 · Organophosphate flame retardants (OPFRs) are common replacements for the phased-out polybrominated diphenyl ethers (PBDEs) and have been detected at high concentrations in environmental samples. OPFRs are structurally similar to organophosphate pesticides and may adversely affect the developing nervous system. This study evaluated the overt toxicity, uptake and neurobehavioral …


2015-2-1 · Hoffman K, Butt C, Chen A, Limkakeng A and Stapleton H (2015) High Exposure to Organophosphate Flame Retardants in Infants: Associations with Baby Products, Environmental Science & Technology, 10.1021/acs.est.5b03577, 49:24, (14554-14559), Online publication date: 15-Dec-2015.


2019-9-30 · Organophosphate flame retardants (OPFRs) are increasingly being used in the home environment as replacements for the phased out polybrominated diphenyl ethers (PBDEs). Several studies utilizing hand wipes and dust samples in concert with urine samples have illustrated that human exposure is occurring in the home environment. While exposure has been


2015-12-2 · More information: Kate Hoffman et al. High Exposure to Organophosphate Flame Retardants in Infants: Associations with Baby Products, Environmental Science & Technology (2015).DOI: 10.1021/acs.est ...


2018-12-1 · High exposure dose, highly vulnerable immune systems, or aged-related exposure behaviors (for example, hand-to-mouth activity) make children aged 0–5 years old, especially infants (0–1 year) and elder children (1–5 years), become susceptible to OPFR exposure (Dourson et al., 2002; Meeker, 2012). Therefore, systematic studies on OPFR exposure and corresponding risk assessment of children and infants …


2021-6-29 · Exposure to Organophosphate Ester (OPE) Flame Retardants & Plasticizers Several classes of flame retardants are used in consumer products. As legacy brominated flame retardants (BFR) are phased-out due to concerns about their bioaccumulation and toxicity, they are increasingly being replaced with OPE flame retardants.


2020-12-23 · Infants a 2211 Newmarket Parkway, Suite 106, ... and household dust. Pre and post-natal exposure causes long term behavioral alterations.5 • Babies’ elevated exposure to PBDEs is linked to high levels of PBDEs in breast milk accounting for infants’ large daily dose ... of organophosphate flame retardants in relation to hormone levels and ...


2014-2-20 · The organophosphate FR chemicals replacing halogenated FR chemicals are structurally similar to organophosphate pesticides. In adults, moderate and high exposure to organophosphate pesticides can cause nerve damage and cognitive problems.15 In infants and children, even much lower levels may harm brain development.16


2020-6-4 · High Exposure to Organophosphate Flame Retardants in Infants: Associations with aby Products. Environ Sci Technol. Dec 15;49(24):14554-9. doi: 10.1021/acs.est.5b03577.


2011-7-1 · Banned flame retardants resurface. Many flame retardants were used in the 1970s in a variety of children's products, such as child car seats, mattresses, and clothing to reduce deaths from fire. Some of these were subsequently banned due to health concerns.


2020-1-1 · Hoffman K, Butt CM, Chen A, Limkakeng AT Jr, Stapleton HM (2015) High exposure to organophosphate flame retardants in infants: associations with baby products. Environ Sci Technol 49(24):14554–14559.


Indoor dust ingestion is one of the main pathways for human exposure to organophosphate flame retardants (PFRs). The urinary concentrations of diesters (DAPs) are usually used as biomarkers to assess human exposure to PFRs. In this study, the PFR and DAP levels were measured in morning and evening urine samp


2015-12-2 · More information: Kate Hoffman et al. High Exposure to Organophosphate Flame Retardants in Infants: Associations with Baby Products, Environmental Science & Technology (2015). DOI: 10.1021/acs.est ...


2015-12-1 · High Exposure to Organophosphate Flame Retardants in Infants: Associations with Baby Products


2015-12-2 · High Exposure to Organophosphate Flame Retardants in Infants: Associations with Baby Products. Environmental Science & Technology , 2015; DOI: 10.1021/acs.est.5b03577 Cite This Page :


2021-7-30 · in very high flame retardant exposures. Others are looking at how a mother and father’s exposure to flame retardants might affect pregnancy outcomes. National Institute of Environmental Health Sciences ... Congleton J, Hoffman K, Fang M, Stapleton HM. 2014. Metabolites of organophosphate flame retardants and 2-ethylhexyl tetrabromobenzoate in ...


Measuring Personal Exposure to Organophosphate Flame Retardants using Silicone Wristbands and Hand Wipes Stephanie C. Hammel†, Kate Hoffman†, Thomas F. Webster‡, Kim A. Anderson§, and ...


2018-8-24 · Human exposure to PBDEs occurs mostly through dust ingestion and is the highest in infants (Johnson et al., 2010; ... Temporal trends in exposure to organophosphate flame retardants in the United States. ... Novel and high volume use flame retardants in US couches reflective of the 2005 PentaBDE phase out. Environ. Sci.


Furthermore, 17% or 21% of inpatient infants had EDIs that exceeded the reference dose, whereas this value was reduced to 13% in outpatient infants; and this value decreased with age among all home-stay children (0-5 years). Our results indicated that inpatient and home-stay infants had a higher potential risk of OPFR exposure.


2016-5-11 · Organophosphorus flame retardants (OPFRs) are used as additives in plasticizers, foams, hydraulic fluids, anti-foam agents, and coatings for electronic components/devices to inhibit flames. These chemicals were developed and used as flame retardants because of environmental and health concerns of previously used brominated and chlorinated flame retardants (FRs).


Inpatients and home-stay infants had high potential risk of OPFR exposure. Abstract Organophosphate flame retardants (OPFRs) have been commonly observed in indoor dust, food, and drinking water in China, but little is known about their exposure levels or factors leading to exposure in Chinese children.


2018-5-1 · It is clear from these studies that pregnant mothers, infants, and children all likely receive significant exposure to organophosphate pesticides. An emerging concern, then, is whether these organophosphate flame retardants pose a developmental neurotoxic risk on par with other organophosphate compounds, such as organophosphate pesticides.


2015-12-15 · Infant products containing polyurethane foam are commonly treated with organophosphate flame retardants (PFRs), including tris(1,3-dichloro-2-propyl)phosphate (TDCIPP) and triphenyl phosphate (TPHP). Infants may have greater exposure due to greater contact with these products, yet little is known about levels of exposure or the factors contributing to higher exposure.


2014-9-19 · Organophosphate flame retardants (OPFRs) are common replacements for the phased-out polybrominated diphenyl ethers (PBDEs) and have been detected at high concentrations in environmental samples. OPFRs are structurally similar to organophosphate pesticides and may adversely affect the developing nervous system.


Infant products containing polyurethane foam are commonly treated with organophosphate flame retardants (PFRs), including tris(1,3-dichloro-2-propyl)phosphate (TDCIPP) and triphenyl phosphate (TPHP). Infants may have greater exposure due to greater contact with these products, yet little is known about levels of exposure or the factors ...


2021-7-1 · the main representatives of organophosphate flame retardants (OPFRs). The exposure of humans to OPFRs present in air, water, and food leads to their occurrence in the circulation. Thus far, no report has been published about the influence of these retardants …


2015-12-2 · “High Exposure to Organophosphate Flame Retardants in Infants: Associations with Baby Products” Environmental Science & Technology. In October, Macy’s joined a growing list of major retail stores that have pledged to stop selling furniture containing flame retardants…


2018-12-1 · Urinary metabolites of organophosphate flame retardants in 0–5-year-old children: Potential exposure risk for inpatients and home-stay infants ☆ Author links open overlay panel Bo Zhang a b 1 Shaoyou Lu d 1 Mingzhi Huang c 1 Meizhou Zhou a Ziqing Zhou a Hangcong Zheng a Yongchen Jiang a Xueyuan Bai a b Tao Zhang a b


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